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The effects on sleep are frequently the very first noticeable marker, sometimes within the first couple of weeks

doi: 10.1007/BF00425152 King, GF, Richardson, DJ, Jackson, JB and Ferguson, SJ (1987)

Major drug Interactions: The pressor effect of sympathomimetic pressor amines is markedly potentiated in patients receiving monoamine oxidase inhibitors (MAOIs) References: Alhashemi JA (2002): Reduction of vasopressor requirement by hydrocortisone administration in a patient with cerebral vasospasm

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The administration periods and cycles vary on an individual basis