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Our findings have several implications for the expanding role of GLP-1 RAs in the management of obesity and cardiometabolic disease that underscore the need to understand patient perceptions to guide clinical decision-making, research, and policy efforts

[67] demonstrated that, in normal human gingival fibroblasts, curcumin can also act as a pro-oxidant: incubation with 1050 M curcumin provoked significant ROS generation, which was accompanied by loss of mitochondrial membrane potential, an early indicator of mitochondrial dysfunction, and externalization of phosphatidylserine, a hallmark of apoptosis

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Lipid peroxidation increases membrane tension, Piezo1 gating, and cation permeability to execute ferroptosis

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