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Moreover, this effect can be reversed by specific GLP-1R (exendin-9) antagonists, which means that GLP-1RA may inhibit the proliferation and differentiation of human adipocyte precursors [97,98]

The function of CDKN1A in cell cycle arrest, which is unable to trigger ferroptosis, is primarily achieved by binding to and suppressing the kinase activity of the cyclin-dependent kinases (CDKs) ( Interestingly, a recent study reported that retention of p53 in the nucleus, mediated by the interaction of long non-coding RNA (lncRNA) P53RRA, and Ras GTPase-activating protein-binding protein 1 (G3BP1), leads to cell cycle arrest, apoptosis, and ferroptosis