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The pharmacokinetics of 2-O-methyl phosphorothioate antisense oligonucleotides: experiences from developing exon skipping therapies for duchenne muscular dystrophy

The American Cancer Society notes that elevated circulating IGF-1 is associated with increased risk of colorectal, breast, and prostate cancers, though causality versus correlation remains debated

Safety Protocols : Clinical trials include detailed safety protocols to address potential risks

PubMed Central, Yue, Xiao, et al

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