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By addressing these factors, patients may experience a holistic improvement in their overall health profile

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some patients achieve excellent results with minimal side effects, while persistent or severe symptoms may indicate a need for dose adjustment

Glycemic control was poor at baseline, as indicated by the high mean glycated hemoglobin level of 8.28%

In comparison, lanifibranor, a pan-peroxisome proliferator-activated receptor (PPAR-//) agonist, achieved significant benefits on both NASH and fibrosis histology in a recent clinical phase 2b study (NATIVE trial) 26