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Changhan David Lee and Pinchas Cohen at the USC Leonard Davis School of Gerontology published the first description of MOTS-c in 2015

Resuscitation with fluids, antimicrobial therapy, peritoneal lavage, and norepinephrine was initiated one hour later to maintain MAP between 6575 mmHg for 12 h

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Exploring Specific MOTS-c Peptide Benefits for Health and Fitness The unique properties of MOTS-c peptide translate into several exciting potential benefits, particularly in the realms of metabolic health, exercise performance, and longevity