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Mice were lightly anesthetized with 0.1 mL of Ketamine/xylazine (200/70 mg/mL) injected intraperitoneally

Additionally, it can inhibit the enzymatic activity of cyclooxygenase and lipoxygenase, leading to a decrease in the synthesis of prostaglandins and leukotrienes (65)

In contrast, drugs modeled after gastrointestinal hormones, such as glucagon-like peptide-1 (GLP-1), have been shown to exhibit fewer side effects while demonstrating high efficacy in obesity treatment

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