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CrossRef HP1 induces ferroptosis of renal tubular epithelial cells through NRF2 pathway in diabetic nephropathy Chuanqiang Zhou, Min Wu, Gaolun Liu, Li Zhou Open Life Sciences.2023;[Epub] CrossRef A Review of the Potential of Nuclear Factor [Erythroid-Derived 2]-like 2 Activation in Autoimmune Diseases Ilker Ates, Aye Didem Ylmaz, Brigitta Buttari, Marzia Arese, Luciano Saso, Sibel Suzen Brain Sciences.2023

Under the excessive accumulation of reactive oxygen species (ROS), over-oxidized PUFA-containing phospholipids (PUFA-PLs) alter the membrane structure and increase its permeability, eventually leading to plasma membrane rupture and cell damage [8]