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Induction of oxidative stress also induced more DNA damage in iPSC-derived C9orf72 motor neurons than controls, in an age-dependent manner (Lopez-Gonzalez et al., 2016)

We also don't know how this drug will interact with other medications and what the long term side effects will be

Efficacy and Safety of Saffron Supplementation: Current Clinical Findings

PlexusDx recommends baseline thyroid labs before starting GLP-1 treatment, then repeat testing at 8 weeks and 16 weeks to catch any necessary adjustments early