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She links increased infection rates to the drug's tempering effect on immune function

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Tachyphylaxis where drugs become less effective over timecreates another key difference

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Eur Cells Mater 23:170181 Huang MJ, Wang L, Jin DD, Zhang ZM, Chen TY, Jia CH et al (2014) Enhancement of the synthesis of n-3 PUFAs in fat-1 transgenic mice inhibits mTORC1 signalling and delays surgically induced osteoarthritis in comparison with wild-type mice