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What it targets Disrupts the FOXO4-p53 interaction so p53 can trigger apoptosis in senescent cells

Dimethyl sulfoxide diluted in a .01 M glycine buffer was added to solubilize the cell membranes and the absorbance of reduced MTT in the buffer was quantitated at 590 nm using a plate reader (Biotek Synergy 2, Winooski, VT)

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