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Pooled analysis showed that tirzepatide 5 mg, 10 mg, and 15 mg were more effective than placebo, with MD in body weight of 7.7 kg (95% CI 11.0, 4.4

Randomized, double-blind trial of triple therapy with saxagliptin add-on to dapagliflozin plus metformin in patients with type 2 diabetes

Within-class comparisons (e.g., semaglutide vs dulaglutide or dapagliflozin vs empagliflozin) also demonstrated no meaningful differences, reinforcing the concept of therapeutic equivalence at the agent level