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However, "more flexibility" does not mean "it doesn't matter." Absorption still varies slightly by site, and at higher dose tiers (10 mg, 12.5 mg, and 15 mg), you want to ensure the medication is being absorbed efficiently

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Animals were anesthetized intramuscularly with a ketaminexylazine mixture composed of 30 mg/kg ketamine and 12 mg/kg xylazine, respectively, with a total injection volume of 1.2 mL/kg

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