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Indirect lesion area was determined by subtracting the intact area of the ipsilateral hemisphere from the contralateral hemisphere

Improved regulation of CBF in response to both transient hyper- and hypotension subsequently protects cerebral microvasculature from hyperperfusive injury and damage as well as ensuring cerebral perfusion is able to match metabolic demand during periods of reduced driving pressures (i.e., orthostatic stress) (Korad et al., 2024

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