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36 Such immunological benefits significantly increase CD4/CD8 ratio in thalassemic patients via increasing total antioxidant capacity/malondialdehyde (TAC/MDA) ratio that takes place via excreting the excess serum oxidants via the percutaneous route

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MEDI7247, an antibody-drug conjugate (ADC) that specifically binds to the extracellular domain of ASCT2, could release its payload pyrrolobenzodiazepine (PBD), promoting DNA damage and tumor cell death (Liu et al., 2018