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When we repeated the experiment with prx1 cells transformed with a plasmid encoding an enzymatically inactive Prx1C91A mutant, we observed no response to the 1 mM bolus of exogenous H 2 O 2 , irrespective of the concentration of H 2 O 2 used in the initial pretreatment (Fig 4C)

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However, insulin follows the path of least resistance when directing glucose, so if muscle tissue receives glucose more easily, it will be preferentially stored there and not in fat

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