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Collectively, evidence for MGBA involvement in PTSD is consistent across human and preclinical studies, with strong mechanistic convergence, while interventional findings, despite early promise, remain preliminary and require validation in larger, controlled trials

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Mazdutide is an investigational unimolecular dual agonist of the glucagon-like peptide-1 receptor (GLP-1R) and glucagon receptor (GCGR), developed as an analog of oxyntomodulin

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