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Author contributions CF: conceptualization and preparing the manuscript text

Species of Desulfovibro promoted gallstone formation in mice To further validate the role of Desulfovibrio species on gallstone formation, we transplanted three commercially available species of Desulfovibrio piger , desulfuricans , and vulgaris to antibiotics-pre-treated GS-S mice

Without intervention, immunosenescence significantly contributes to morbidity and mortality among the elderly, intensifying healthcare burdens and diminishing quality of life on both individual and societal levels

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