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Copper serves as an essential cofactor for over a dozen so-called cuproenzymes, including superoxide dismutase (SOD) for antioxidant defense, lysyl oxidase for collagen cross-linking, and cytochrome c oxidase for cellular respiration

NLRP3 is also considered a key regulator of intestinal inflammation in humans, as exemplified by conditions such as Crohns disease

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31 Lastly, a longer-acting synthetic derivative of GLP-1, liraglutide, is in the pipeline

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