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Of importance, GLS inhibition and IDH1 mutations are synthetically lethal under oxidative stress, and GLS inhibition with CB-839 has been shown to selectively radiosensitize the IDH1 mutated xenograft GBM tumors [159]

Noormohammadi Z, Arghavani H, Javanbakht M, Daneshpazhooh M, Jalali M

In severe cases, lesions may even be observed in the thalamus, basal ganglia, midbrain, hippocampus, and cerebral cortex (McMillan et al., 2023).The pathologic hallmarks of JEV-infected patients are neuron loss and microglia activation (Liao et al., 1998)

De esta manera, puede decirse que su funcin principal es actuar sobre el metabolismo del cuerpo, generando energa y utilizando las grasas para ello