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Informe a su mdico si cualquiera de estos sntomas es grave o no desaparece: manchas de grasa en la ropa interior o en la ropa gases con manchas aceitosas necesidad urgente de defecar heces blandas heces aceitosas o grasas aumento del nmero de evacuaciones dificultad para controlar las evacuaciones dolor o molestias en el recto dolor de estmago periodos menstruales irregulares dolor de cabeza ansiedad Algunos efectos secundarios pueden ser graves

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Before initiating JANUMET, ask patients about a history of heart failure or other risk factors for heart failure including moderate to severe renal impairment

While we often associate sleep with impacting cognitive health or even metabolic health, its less appreciated in relation to the health and quality of our muscle tissue