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Appetite effects: Act on brain regions controlling hunger and fullness Reduce appetite between meals Enhance feelings of satisfaction after eating Decrease food preoccupation and cravings Gastric effects: Slow stomach emptying Prolong feelings of fullness Reduce the volume of food needed to feel satisfied Metabolic effects: Improve insulin secretion (glucose-dependent) Reduce glucagon release Improve insulin sensitivity Both Saxenda and Ozempic work through these mechanisms

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doi: 10.1111/jsr.12674 80