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Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus

You can compare this to cyanocobalamin which requires extra steps to be used by the body assuming it actually makes it into the body through the gut

One domain senses the glutathione, and the other transports it. The proteins unique structure may explain its abilities, says Birsoy

It alters brain chemistry by inhibiting the reuptake of dopamine, norepinephrine, and serotonin the same neurotransmitters that regulate appetite, reward, mood, and energy

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