These changes happen within the body
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Later, a Science investigation raised suspicions, presenting evidence that Sylvain Lesn, a professor in UMN's Department of Neurology, who was Ashe's protg and the paper's first author, used manipulated data not only in the Nature paper but in other publications as well
Global deprotection and cleavage of the peptides from the solid-support resin were achieved using a CEM Razor instrument via a 40-min incubation at 40 C in a mixture of 95% trifluoroacetic acid, 2.5% triisopropylsilane, and 2.5% water
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