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F., Jr, Noben-Trauth, N., Schopf, L., Madden, K

Selenometabolomics: identification of selenometabolites and specification of their biological significance by complementary use of elemental and molecular mass spectrometry

Lim et al., 2016)

The Collateral Damage: Allopregnanolone Allopregnanolone (ALLO) is synthesized in the brain from progesterone via a two-step pathway: Progesterone 5-dihydroprogesterone (via 5-alpha reductase) 5-DHP Allopregnanolone (via 3-HSD) Because 5-AR is the rate-limiting step, inhibiting it blocks ALLO productioneven when progesterone levels are adequate

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