Its also why doctors evaluate other factors such as sleep apnea, thyroid issues, and insulin resistance when discussing sermorelin as a peptide therapy
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You take it
The peptide's primary mitogenic actions involve stimulation of the MAPK/ERK pathway, which promotes cell cycle progression, and the PI3K/Akt pathway, which enhances cell survival and prevents apoptosis
The selectivity is documented in the foundational paper: a peer-reviewed European Journal of Endocrinology study demonstrating that Ipamorelin stimulates growth hormone selectively without elevating ACTH, cortisol, or prolactin, which is exactly why it has become the default selective secretagogue in modern peptide medicine
