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Procedures used to generate Bmal1 lox/lox / Pax8-rtTA /LC-1 Cre mouse strain (bred on the genetic background of the C57BL/6J mouse from The Jackson Laboratory) were described previously (12)

The plasma parameter log (TG/HDL-C) as an atherogenic index: correlation with lipoprotein particle size and esterification rate in apoB-lipoprotein-depleted plasma (FER(HDL))

Selecting the preserved formulation allows for multiple punctures over a 28-day beyond-use window post-opening, whereas the preservative-free formulation provides a pure, additive-free profile for high-dose or high-sensitivity applications

Costs vary depending on insurance, pharmacy choice and program eligibility