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Insurance coverage of GLP-1 medications for obesity has invariably been relatively poor across all markets, including commercial and Medicaid

For many on a weight management plan, the eventual goal is to phase out the use of semaglutide or tirzepatide

Regional Insights North America GLP-1 Receptor Agonist Market Insights North America dominated the global GLP-1 Receptor Agonist Market in 2025 with approximately 45% of global revenues, anchored entirely by the United States' unique drug pricing environment and the commercial investment that Novo Nordisk and Eli Lilly have made in building GLP-1 prescribing across endocrinology, primary care, cardiology, and bariatric medicine

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