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Loren Pickart [7]

Therefore, the infiltration of macrophages into the large intestine of the Si-DSS group was significantly less than those of the Con-DSS group in which the colon plicae and the rectal crypt structure were almost destroyed

In parallel, IGF-1 may also promote expansion of Leydig cell mass and/or support their functional maturation, perhaps through modest mitogenic or differentiation-supporting pathways