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Reducing the proliferation of breast cancer cells by blocking this cascade, which was accomplished by lowering the expression levels of YAP gene targets (63)

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Ligand-stimulated FLNA binding results in the disruption of the SSTR2-p85 complex and the subsequent inhibition of PI3K (88)

Supporting this notion, wildtype mice injected with A oligomers exhibit both depressive-like behaviors and microglial activation in the cortex and hippocampus, as well as aberrant TNF- signaling (Torrisi et al., 2019)