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Some studies have shown that Bivalirudin seemed to be more efficacious and safer than unfractionated heparin(UFH) for patients undergoing ECMO and a significant reduction in the transfusion requirements of composite blood products in pediatric patients on ECMO (79, 80)

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Davidson MM, Nesti C, Palenzuela L, Walker WF, Hernandez E, Protas L, et al

The collagen matrix that provides structural support simply cannot contract fast enough to keep pace with dramatic fat reduction