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Our search strategy included both free-text and Medical Subject Headings (MeSH) terms, utilising the keywords tirzepatide, ly3298176, semaglutide and nn9535 (electronic supplementary material [ESM] Table 1)

For more on treatment duration, see our guide on how long to stay on semaglutide

GLP-1 is a hormone produced in the small intestine that stimulates insulin sensitivity and inhibits glucagon secretion, thereby lowering blood sugar

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Understanding how each drug works and what distinguishes semaglutide vs tirzepatide can help individuals and clinicians make informed choices about treatment options