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a , Top, RMSF values of alpha carbons computed during MD simulations of the GLP-1RGLP-1G s complex (black line) and the GLP-1RTT-OAD2G s complex (red line)

The abundance of selected transcripts was also analyzed in gene-chip experiments

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1 Introduction Osteoarthritis (OA) is a highly prevalent and destructive degenerative joint disease, affecting approximately 7.6% of the global population, with over 595 million cases in 2020 alone (Martel-Pelletier et al., 2016