In preclinical IBD models using nanoparticle delivery, KPV reduces inflammation, normalizes epithelial barrier markers, and lowers cytokine load
Activity modification: Modifying activities that exacerbate symptoms, such as avoiding high-impact exercises or prolonged sitting, can help reduce strain on the gluteal tendons and promote healing
There is no absolute contraindication to using these medicines together, and no official pharmacological interaction has been documented that would prevent their concurrent use

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Umbrello et al., 2013)