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A recent AMA/CDC report covered the challenges with long term adherence and the introduction of new indications will drive the need for ongoing research incorporating richer data sources beyond claims

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79 While the direct renoprotective mechanisms of GLP-1RAs are still under investigation, their ability to enhance natriuresis and suppress pathogenic angiotensin II production presents a valuable therapeutic strategy in HFpEF complicated by CKD

When it comes to obesity, Seeley said, your flavor of metabolic disease will be different than the next persons. Obesity drugs of the future may finally reflect that diversity, too