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Bains JS, Shaw CA

While the precise molecular intermediaries and signaling pathways remain to be clarified, ipamorelins influence on bone-associated endocrine loops (involving growth hormone and maybe local IGF-I) is plausibly central, potentially altering the balance between bone-forming and bone-remodeling processes at the tissue level

People who are pregnant or breastfeeding, have thyroid or kidney problems, or are taking medications that may not mix well with L-carnitine should avoid it unless advised by a doctor

Ethics statement This study was approved by the Human Research Ethics Board (HREB) at the University of Alberta (protocol # Pro00099502)

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