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A summary of the key preclinical and clinical findings on GLP-1RAs and DPP-4is in neuropathic pain models is presented in Table 1, highlighting their proposed mechanisms of action and therapeutic outcomes across various studies

While delayed gastric emptying is most prominent in the initial period of GLP-1 RA therapy, studies showing normalization of gastric emptying remain uncertain (Ushakumari and Sladen 2024)

Typical results Most patients see gradual but steady progress

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