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13 1 92 2025 May Structural pharmacology and mechanisms of GLP-1R signaling

doi:10.1016/j.cmet.2022.07.013 Giblin K, et al

Gesamtmortalitt Meta-Analysen ber 13 groe Studien (83.258 Patient:innen) belegen: GLP-1-Medikamente senken die Gesamtsterblichkeit signifikant unabhngig von Geschlecht, BMI oder Vorerkrankungen

Consistent with this, following a meal the venous blood pyruvate/lactate exiting human muscle was 12% more reduced compared to the arterial blood pyruvate/lactate entering muscle, while during long-term fasting the venous blood pyruvate/lactate exiting muscle was 28% more reduced than the arterial blood entering (Aoki et al., 1975)