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Preclinical Studies Early preclinical studies in rodent obesity models demonstrated that AOD9604 administration reduced body weight and fat mass without affecting food intake, indicating a direct metabolic effect rather than an appetite-suppressing mechanism

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Later reactivation (within hours) of the neuronal network surrounding tagged synapses promotes the capture and translation of Plasticity Related Products (PRPs) leading to a final stabilization of synaptic weight change while maintaining input-specificity (Redondo and Morris, 2011)

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In the beginning, the elderly had 55.2% less glycine and 24.4% less cysteine in their red blood cells