Semaglutide in pill form, currently available as Rybelsus for Type 2 diabetes, is outright not recommended while breastfeeding, the prescribing information says

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Although de novo polyamine synthesis from ornithine represents the major source of intracellular polyamines, transport of extracellular polyamines into cells is accomplished via the SLC45A4 encoded transporter which is a member of the glycoside-pentoside-hexuronide cation symporter family of transporters
The reduction in attack frequency and improved quality of life observed supports the efficacy of Lanadelumab and emphasizes the need for genetic testing to guide treatment decisions
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