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The metabolically stabilized 6-AH family member, D-Nle-Tyr-Ile-NH-(CH 2 ) 5 -CONH 2 , had a t| /2 in blood of 80 min compared to the parent compound Norleual (Nle-Tyr-Leu-T-(CH 2 -N) 3 -His-Pro-Phe, SEQ ID NO: 1), which had a tj 2 in blood of Cm ax concentration in plasma extrapolated to time zero (Co), terminal elimination half-life (ti 2 ), volume of distribution (Vd), and clearance (CL)

Trube G, Rorsman P, Ohno-Shosaku T

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2.12 Statistical analysis and experimental design A fully randomized experimental design was used in this investigation, including four replicates for every treatment

HGF dimenzes or multimenzes and that under physiological circumstances this process is required for its activation and ultimately the activation of its receptor, c-Met