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This hydrolysis, catalyzed by BSHs from genera such as Lactobacillus , Bifidobacterium , Bacteroides , and Clostridium , releases free BAs along with glycine or taurine (91)

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CRP caused mechanical and thermal hyperalgesia in rats after intraplantar injection, and overexpression in the dorsal root ganglion (DRG) correlated with increased pain behaviors, indicating a potential role for CRP at the DRG level in modulating nociceptive signaling (Liu et al., 2023)

But our findings still indicate a need for careful evaluation of the implications of anemia in CC