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The less favorable effects, she said, include hair thinning and excess skin

Neuro-ophthalmology encompasses the spectrum of neurologic, ophthalmic, and systemic disorders affecting the optic nerve, central visual pathways, or neural control of eye movements

Any observed reductions in inflammation likely reflect improved metabolic control rather than specific anti-rheumatic effects

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Because IGF-I exerts anti-inflammatory actions and is important for peripheral glucose uptake, metabolic disturbances in these patients can, in part, be explained by the low IGF-I levels (83)