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Published AOD-9604 trials did not report patterns of fluid retention or edema, suggesting this side effect is not a concern with the peptide fragment

The same research discusses the actin-binding site and angiogenesis-related activity in study models

It has some of the strong ingredients like zinc, niacinamide, glycerine and biosaccharide gum which are known for brightening the skin

Front Physiol 13:983961

The findings imply that there could be possible therapeutic benefits from CBM588, although confirmation is needed from larger, placebo-controlled trials (Miyaoka et al., 2018)