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activation of PI3K/AKT downstream pathway driving synaptogenesis and anti-apoptotic effects in hippocampus Regulatory status: not approved by the FDA or EMA

Explored in research involving sarcopenia, osteoporosis, and age-related muscle loss

Despite promising preclinical data, clinical translation of senotherapeutics remains hindered by SnC heterogeneity, off-target toxicity, variable efficacy across models, and lack of robust biomarkers

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Additionally, vegans and vegetarians are likely to require supplementation of L-Carnitine since they will not be able to obtain it from food sources