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IGF-I in animal models of muscle wasting, neuromuscular disorders and injury Sarcopenia Sarcopenia is caused by a multitude of factors which include chronic inflammation, blood vessel dysfunction, denervation, malnutrition, physical inactivity, and is characterized by decreased muscle strength and selective type II fast fiber atrophy

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Thus in presence of LC, it was suggested that PGE 2 plays a role in the mechanistic pathway leading to endometriosis, while PGE 1 may potentially be involved in suppressing the production of immune cells and inflammatory response [29]

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