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After a single dose of desogestrel/ethinyl estradiol combination tablet [dark blue], the relative bioavailability of ethinyl estradiol is approximately 93% while the relative bioavailability of the 0.01 mg tablet [green] is 99%

In the stress-sedentary model, researchers conducted pharmacodynamic assessments using endurance running, a nontraditional pharmacologic tool, and observed an ameliorative effect on neurexins- and neuroligin 1 expression and synaptic plasticity [54]

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Because microdosing uses lower doses than a standard weight loss program, many patients find the adjustment period easier to manage