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As another important component of the opioid system, there are three main canonical opioid receptors, namely , , and opioid receptors (MOR, DOR, and KOR, respectively), which play important roles in various physiological and pathological functions of the body (Table 1), as well as the nociceptin/orphanin FQ receptor (NOR), which was previously known as opioid receptor-like-1, and are widely distributed in systemic cells [12,13]

When glucose levels are high, GLP-1 and GIP work in tandem to reduce the alpha-cell release of glucagon, thereby aiding in glucose regulation

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-Glutamyl Transpeptidase is one of many peptidases that cleave terminal peptide bonds of proteins or peptides

The body, in its search for energy, can begin to catabolize muscle tissue