David Sinclair, a leading voice in longevity research, has stated: NAD+ is the closest we've gotten to a fountain of youth.[2] His research highlights how NAD+ activates pathways that mimic caloric restriction, a known extender of lifespan in models
B12 deficiency is especially risky for vegetarians, the elderly, and people with absorption issues, such as those with Crohns disease.
Trade-offs include less flexibility in dose adjustment and prolonged exposure if adverse effects develop
Cyanocobalamin is the most widely used form of Vitamin B12, and has hematopoietic activity apparently identical to that of the antianemia factor in purified liver extract
Post-injection care is straightforward: Stay hydrated for the remainder of the day Avoid rubbing or massaging the injection site aggressively Apply a cold compress if swelling or soreness develops at the injection site Monitor for signs of allergic reaction (hives, difficulty breathing, dizziness) for at least 30 minutes Contact your provider or seek emergency care if you experience chest tightness, significant swelling, or breathing difficulty Strenuous exercise can resume the same day for most patients, though some prefer to wait until the following morning if injection-site soreness is noticeable