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In humans, even slight chronic exposure to low levels of methanol (0.871.0%) associated with severe malnutrition, especially in conjunction with a deficiency of cobalamin (vitamin B12) and folic acidvitamins involved in the metabolism of methanol and its metabolites, can have dramatic consequences and result in the development of optic neuropathy

Additionally, this supports the increased circulating GLP-1 levels observed in Glp1r / mice (Lamont et al., 2012), albeit the intact receptor is required for improved post-prandial lipid tolerance

10.1002/ldr.4989 38 KuppusamyS.PalanisamiT.MegharajM.VenkateswarluK.NaiduR

Peer review Peer review information Nature Reviews Endocrinology thanks Noel Morgan